This report is aimed at outlining strategies for preventing and responding to violence in the lives of children. The report is intended for policy-makers and decision-makers who can carry out these strategies. The report includes descriptions of interventions that address interpersonal violence against children in several settings, including home and school, but not in the contexts of natural disasters or armed conflict. The six strategies featured in the report are: (1) supporting parents, caregivers and families; (2) helping children and adolescents manage risks and challenges; (3) changing attitudes and social norms that encourage violence and discrimination; (4) promoting and providing support services for children; (5) implementing laws and policies that protect children; (6) carrying out data collection and research.