The purpose of this conference is to showcase recent biological advancements related to child maltreatment and other forms of trauma and chronic stress. Three distinct sessions will cover processes of biological embedding emphasizing the role of the endocrine system/immunology, brain development and genomics. A fourth session will focus on resilience from a multi-level, multidisciplinary perspective. The conference will culminate in a panel discussion of the data and ideas presented in these four sessions where discourse among panel and audience members will be encouraged.