In this commentary piece, Aisha K Yousafzai - of the Department of Global Health and Population at the Harvard TH Chan School of Public Health and the and Department of Paediatrics and Child Health at Aga Khan University - notes that "the evidence presented [in the Lancet Group Commission on the institutionalisation and deinstitutionalisation of children] and their call to action to ensure abandoned children can thrive in family-based care environments rather than in institutions matters now more than ever as the global community addresses unprecedented challenges to ensure a generation of children are not left behind with respect to their survival, health, development, learning, and safety."