Catholic Medical Mission Board Zambia (CMMB), SPOON, and St. Catherine's University conducted this Health Impact Assessment (HIA) in Lusaka Province, Zambia, to understand the disparate impact that COVID-19 and the containment measures had on children with disabilities and their families. his two-phased assessment is designed to gather evidence about the impact through seven domains: COVID-19 knowledge and practices, food consumption, housing and livelihood, child safety and risk of separation, child health and wellness, parental and child stress, and education.