This article highlights the devastating impact of the ongoing Ebola outbreak in eastern Democratic Republic of Congo, including the deaths of children living in orphanages and other vulnerable settings. It follows the story of a 6-month-old girl who became the third child from her orphanage to die from the virus, illustrating the heightened risks faced by children without parental care during health emergencies. The article also examines the challenges of containing the outbreak, including strained health services, community mistrust, and the difficulties of protecting children and caregivers in affected communities.