This Lancet commentary highlights a major update to the evidence base for preventing violence against children, emphasizing findings from a new systematic review that strengthens and refines the INSPIRE Framework’s intervention strategies. It underscores that several approaches—such as parenting programs, whole-school violence prevention, healthy relationships education, and cash-plus life-skills initiatives—are proven effective, while others lack sufficient evidence and require reevaluation. The authors call for greater investment in research, especially in low- and middle-income and humanitarian contexts, stronger alignment between violence against children and violence against women prevention efforts, and sustained financing to scale effective interventions. Overall, the piece urges bold, evidence-driven action to protect children and fulfill global commitments to end violence.
