CTWWC Guatemala helps children currently living in residential care facilities (referred to as protection homes in Guatemala). The initiative does this through: reforming the care system at the national level, strengthening families and commmunities, and advocacy and awareness efforts.

CTWWC Guatemala works at the national level with the four responsible government institutions to build programs and services for children and families including prevention of separation/ family strengthening, case management for reintegration, family-based alternative care, and more. CTWWC Guatemala connects families with community support and existing social services and ensures children are cared for in safe and nurturing families and has adapted to emergency response under COVID. 

CTWWC Guatemala trains government staff charged with child protection and care, mentors workers to provide quality case management, conducts research to inform national care reform policy and practice, analyzes state budgets and provides cost comparisons to advocate for family care. CTWWC Guatemala works closely with government and nongovernment partners to prevent unnecessary family separation and promote support services for families, expand family-based alternative care such as kinship care and temporary foster care, ensure children's quality care as related to migration, planned reunification of children from residential care into family-based care, transition or transformation of residential care models (protection homes) to community and family services.

CTWWC Guatemala makes learning from the work in the country available to other countries and organizations via webinars, training and exchanges.