This report reviewed evidence for the effects of psychosocial neglect on development derived from studies of young children raised in U.S. institutions. In these caregiving environments, children are physically safe and receive instrumental care, but the social, emotional, and cognitive components of caregiving are impoverished. The damaging and often lasting effects of these caregiving environments on young children's development underscore that psychosocial neglect should be considered as dangerous to child well-being as physical maltreatment.