Through an analysis of the impact of the pandemic on the Italian and Greek reception systems and social interventions with unaccompanied minors (UAMs), the authors of this study utilised a multiple embedded case study approach within a comparative analysis, to identify key changes in the main services which should be guaranteed to minors—namely, hosting/housing, guardianship, foster care, family/relatives reunification, school integration, language, job training for care leaving, and preparation for leaving care after 18 years.